ISOSORBIDE DIMETHYL ETHER

PRODUCT IDENTIFICATION

CAS NO. 5306-85-4

5306-85-4

EINECS NO. 226-159-8
FORMULA C8H14O4
MOL WT. 174.20

H.S. CODE

2932.99

TOXICITY

SYNONYMS 1,4:3,6-dianhydro-2,5-di-O-methyl-D-glucitol;
1,4:3,6-dianhidro-2,5-di-O-metil-D-glucitol; 1,4:3,6-dianhydro-2,5-di-O- méthyl-D- glucitol; 2,5-Di-O-methyl-1,4;3,6-dianhydro-D-glucitol;
SMILES

 

CLASSIFICATION

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE

clear oily liquid

MELTING POINT  
BOILING POINT 93 - 95 C at 0.1 mm Hg
SPECIFIC GRAVITY

1.15 - 1.17

SOLUBILITY IN WATER  
pH  
VAPOR DENSITY

 

AUTOIGNITION

 

NFPA RATINGS

 

REFRACTIVE INDEX

1.461

FLASH POINT

 

STABILITY Stable under ordinary conditions. Hygroscopic.

APPLICATIONS

Isosorbide is a bicyclic ether derivative of glucitol. The nitric acid esters of isosorbide are used as osmotic diuretic to reduce intraocular pressure with effects on both arteries and veins and to treat coronary insufficiency and angina pectoris. The monoester is a white crystalline powder; melting point  140 C; freely soluble in water, alcohol and chloroform. The diester is a white crystalline powder; melting point  70 C; sparingly soluble in water; soluble in organic solvents (acetone, alcohol, ether); administered sublingually and orally. Diester is a explosive. It should be diluted (25 - 40%) with lactose or mannitol for transportation. Chemical designation is 1,4:3,6-dianhydro-D-glucitol mono (di) nitrate.
SALES SPECIFICATION

APPEARANCE

clear oily liquid

PURITY

99.0% min

WATER

0.1% max

HEAVY METALS

20ppm max

TRANSPORTATION
PACKING
200kgs in Drum
HAZARD CLASS  
UN NO.  
OTHER INFORMATION
Hazard Symbols: , Risk Phrases: , Safety Phrases: 23-24/25